Encephalitis simply means brain inflammation.
The inflammatory reaction not only damages tissue, but also the
microcirculation small arteries capillaries and particularly small
veins. The damage to the blood supply is the main determinant of
recovery because of oxygen transport limitation.
The result is that brain tissue can remain in
suspended animation "not dead but sleeping" - simply because of the
increased tissue water - edema - chronically preventing adequate
oxygenation. The best analogy is a comparison with an electrical
Imagine coupling a transistor radio - which requires a
9-volt battery to a 6-volt battery - it simply will not work - even
if the six-volt battery is capable of delivering thousands of
amperes - like a submarine battery.
There is nowhere on the surface of this planet
that breathing air the oxygen level (voltage) in plasma can exceed
about 100 (mm Hg).
In a hyperbaric chamber breathing pure oxygen,
the level can be increased to over 2000 (mm Hg). This simple and
completely scientific explanation for the need for hyperbaric
conditions is UNKNOWN to the overwhelming majority of physicians -
hence oxygen is not properly used.
Neurologists have recognized the need for
oxygen. Three of the most eminent neurologists/neurosurgeons of the
80's stated in relation to the ischemic penumbra.
"Presumably the critical parameter for tissue
function is oxygen availability rather than blood flow." Using
hyperbaric conditions allows a decoupling of blood flow and oxygen
Astrup J, Siesjo BK, Symon L. "Thresholds in
cerebral ischemia -the ischemic penumbra." Stroke 1981;12:723-725.
Therefore, if we are to discover if there is recoverable brain
tissue we need to reoxygenate. Dr Richard Neubauer has used SPECT
imaging to demonstrate this effect and the work is published e.g.
Lancet March 3 1990.
Dr Philip James