Jiang Yunshen, Yu ping, Song ling, Zhang Yanzhi, Wang Xinru
explore the effect of hyperbaric oxygen (HBO) on type I allergic
reaction and some parameters of immune function. Test animals (rats,
mice, rabbits) were divided into two HBO groups (HBO treatment for 5
or 10 days) and control group. The HBO treatment was pure oxygen
(99.5%) inhalation for 2 hours each day under 0.20 Mpa abs pressure.
Then the evidence of type I allergic reaction and changes of some
immune function indexes were measured and analyzed.
HBO treatments alleviate homo-passive skin allergic reaction
in rat and hetero-passive skin allergic reaction in mice. It also
inhibited the thyroxin induced mast cell degranulation in mice and
markedly reduced peripheral blood T-lymphocyte in rabbits, and
significantly decreased the number of antibody producing cells in
HBO treatments were shown to prevent the occurrence or
alleviate the type I allergic reaction in the Laboratory animals.
Both the cellular immune function and body fluid immune function
were inhibited remarkably.
Key Words: Hyper-baric oxygen, Immune, Type I